Core Nutritional

Vitamin E — 134 mg (200 IU)

💊 What it does

Vitamin E is a fat-soluble antioxidant that protects cell membranes from oxidative damage by neutralising free radicals. Alpha-tocopherol is the most active form in humans. It works synergistically with vitamin C (which regenerates oxidised vitamin E) and selenium. Vitamin E supports immune function, skin integrity, and cardiovascular health. It is found abundantly in plant oils, nuts, and seeds — deficiency is uncommon in people eating adequate dietary fat.

👤 Who needs it

People with fat malabsorption conditions (Crohn's disease, cystic fibrosis, liver disease). Those on very low-fat diets. People with rare genetic conditions affecting vitamin E transport. Most people eating a varied diet with adequate healthy fats get sufficient vitamin E from food without supplementation.

🥦 Food sources first

Excellent plant sources: sunflower seeds and sunflower oil, almonds, hazelnut oil, avocado, pine nuts, peanuts, spinach, Swiss chard, butternut squash. Wheat germ oil is extraordinarily rich. Most nut and seed-based diets provide plentiful vitamin E. Deficiency in someone eating adequate nuts, seeds, and plant oils is very uncommon.

🗓 When to supplement

Primarily for people with fat malabsorption conditions. For general antioxidant support in people with limited nut and seed intake. Not needed by most people eating a varied plant-based diet.

🏷 Best form to look for

Natural d-alpha-tocopherol (often labelled as d-alpha, from natural plant sources) has approximately twice the biological activity of synthetic dl-alpha-tocopherol (often labelled as dl-alpha). Mixed tocopherols and tocotrienols provide broader antioxidant coverage and may be superior to isolated alpha-tocopherol alone.

⏰ When to take it

With a meal containing fat — vitamin E is fat-soluble.

⚡ Interactions & combinations
High-dose vitamin E (above 400 IU/day) has been associated with increased all-cause mortality and increased haemorrhagic stroke in some large trials — do not mega-dose. Mild antiplatelet (blood-thinning) effect — relevant for people on warfarin or anticoagulant medications. May interact with chemotherapy at high doses.
🛡 Safety notes
The UK upper limit is 540 mg/day (800 IU). High-dose supplementation (above 400 IU/day) is not recommended without specific medical reason — the evidence does not support benefit and suggests potential harm at megadoses.
🌿 Vegan note
Natural vitamin E (d-alpha-tocopherol) is derived from plant oils (soya, sunflower, palm — though palm sourcing raises sustainability concerns). Synthetic dl-alpha-tocopherol is also plant-based. Mixed tocopherols are plant-derived.
Moderate evidence
Good evidence, though not unanimous across all research.
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Disclaimer: As with any supplement, it is best to consult with a healthcare professional before starting, particularly if you are pregnant, nursing, or taking prescription medications.