Adaptation
The body's gradual adjustment to a new eating rhythm — gas subsides, hunger calms, and energy stabilises as the metabolic system recalibrates. Typically 2–3 weeks. Not a sign of failure.
Amino Acids
The molecular building blocks of protein — 9 are "essential" (must come from food). Used for muscle repair, enzyme production, hormone signalling, and immune function. Deficiency during fasting contributes to fatigue, poor recovery, and hair thinning.
Autophagy
The cellular recycling process — cells dismantle and reuse damaged proteins, worn-out mitochondria, and accumulated debris. A continuous background process; fasting may increase its activity by reducing competing signals from incoming nutrients.
Blood Sugar Stability
Maintaining steady glucose levels without large spikes and crashes — the foundation of stable energy, mood, and appetite. Achieved through whole-food carbohydrates, adequate protein and fibre, and structured meal timing.
Brain Fog
A subjective sense of reduced mental clarity, slow thinking, or poor concentration. A common driver is unstable blood sugar from refined carbohydrate cycles. Structured fasting can reduce glucose spikes, often improving mental steadiness.
Cortisol
The primary stress and energy-mobilisation hormone — rises during fasting to help release stored fuel. In small doses, it supports alertness. Chronically elevated cortisol from over-fasting or life stress disrupts sleep, immunity, and hormonal balance.
Eating Window
The daily time period during which meals are consumed in time-restricted eating — e.g., 8 hours (16:8) or 10 hours (14:10). Should be generous enough to meet full nutritional needs.
Electrolytes
Minerals — sodium, potassium, and magnesium — that regulate fluid balance, nerve signalling, muscle contraction, and heart rhythm. Shift during fasting; low intake causes headaches, dizziness, cramps, and fatigue.
Fat Adaptation
The metabolic state in which the body has become efficient at using stored fat and ketones as fuel between meals — reducing dependency on constant incoming glucose. Develops gradually over weeks of consistent eating rhythms.
Fasted State
The physiological period between meals when digestion has quietened, insulin is lower, and the body can access stored fuel more readily and redirect attention toward internal maintenance.
Fed State
The physiological period after eating when digestion is active, insulin is elevated, and the body is in building and storing mode.
Food Noise
Persistent background mental focus on food, cravings, and eating decisions. Structured fasting and stable blood sugar often reduce food noise, creating a sense of mental clarity and freedom from constant food-related thought.
Fuel Switching
The body's ability to transition between using incoming glucose (fed state) and stored energy — glycogen and fat (fasted state) — without crashing. Improves with metabolic flexibility from structured eating rhythms.
Glucose-Lowering Medication
Drugs that reduce blood sugar — insulin injections, sulfonylureas, and other agents. Dosed assuming regular meals; fasting without dose adjustment can cause dangerous hypoglycaemia. Requires medical supervision.
HbA1c
Glycated haemoglobin — a blood test reflecting average blood glucose over the past 2–3 months. Used to diagnose and monitor diabetes and prediabetes. A simple pre-fasting safety check for anyone with suspected blood sugar issues.
Hypoglycaemia
Dangerously low blood glucose — symptoms include shaking, sweating, confusion, loss of coordination, and fainting. In severe cases: seizures. A real risk for people on glucose-lowering medications who fast without medical supervision.
Insulin
The pancreatic hormone that moves glucose from the blood into cells. Also acts as the master "storage" switch — when elevated, stored fat is less accessible. Fasting allows insulin to fall naturally, restoring access to stored fuel.
Insulin Resistance
When cells become less responsive to insulin's signal, requiring higher insulin levels to achieve the same glucose uptake. The root cause of prediabetes and Type 2 Diabetes — driven by refined carbohydrates, inactivity, poor sleep, and chronic stress.
Insulin Sensitivity
How effectively cells respond to insulin's signal. High sensitivity = efficient glucose clearance; low sensitivity (insulin resistance) = more insulin needed. Improved by structured fasting, exercise, sleep, and whole-food nutrition.
Ketones
Fat-derived molecules produced by the liver during fasting when insulin is low — an alternative fuel source for the brain. Some people experience calm focus; others feel discomfort initially during adaptation.
Medical Supervision
Guidance from a qualified clinician when fasting is combined with medical conditions or medications. Non-negotiable for anyone on glucose-lowering drugs or with a history of hypoglycaemia.
Metabolic Flexibility
The body's ability to switch smoothly between glucose and fat/ketones as fuel without crashing or experiencing urgent hunger. Developed through structured eating rhythms and whole-food nutrition.
Microbiome
The ecosystem of trillions of bacteria in the large intestine — responding to both food quality and meal timing. Fasting windows allow the Migrating Motor Complex to run; fibre feeds the bacteria. Both matter.
Migrating Motor Complex (MMC)
A sweeping wave of muscular contractions moving through the stomach and small intestine between meals — clearing food residue, relocating bacteria, and preventing stagnation. Only activates when eating stops; even small snacks interrupt and reset the cycle.
Mitochondria
The energy-producing organelles inside cells — converting glucose and fatty acids into ATP. A primary target of cellular maintenance (autophagy); older, less-efficient mitochondria are recycled and replaced during fasting windows.
Nutrient Density
The concentration of essential nutrients (protein, vitamins, minerals, fibre) relative to calories. Nutrient-dense foods — legumes, leafy greens, eggs, berries — provide the raw materials for repair; ultra-processed foods provide calories without materials.
Overnight Fast
A fasting window spanning the sleeping hours — typically 12–16 hours from the last evening meal to the first morning meal. The most practical and sustainable fasting approach; already built into healthy human sleep rhythms.
Rebound Hunger
Strong, urgent hunger following aggressive restriction — driven by under-protein meals, breaking fasts with sugar, or fasting windows that exceed the body's current adaptation level. Resolved by shortening the fast and fixing first-meal structure.
Refeeding
The process of breaking a fast. The first meal after a fast strongly influences blood sugar stability, gut comfort, and the next several hours of energy. Best practice: protein + fibre + minerals first.
Repletion
Restoring nutrient reserves — protein, minerals, vitamins — before introducing fasting restriction. The Nutriofia principle: nourish first, then create space. Fasting on a depleted system amplifies symptoms.
Stabilisation Phase
A period of focusing on nutrition, sleep, and meal structure before extending fasting windows. Not a setback — intelligent calibration that makes subsequent fasting more effective and comfortable.
Sulfonylureas
A class of oral diabetes medication that stimulates insulin secretion regardless of blood glucose — particularly dangerous during fasting. Require clinician-supervised dose adjustment before any fasting protocol begins.
Thyroid
The gland that regulates metabolic speed. Sensitive to prolonged calorie restriction — severe under-eating can slow thyroid output as a survival response, causing fatigue, cold intolerance, and low mood.
Time-Restricted Eating (TRE)
A daily eating pattern where food is consumed within a consistent window (8, 10, or 12 hours). The most practical and evidence-supported form of intermittent fasting — achievable simply by shifting dinner earlier or breakfast later.